NEUROSCIENCES AND NEUROANAESTHESIA Do we need inhaled anaesthetics to blunt arousal, haemodynamic responses to intubation after i.v. induction with propofol, remifentanil, rocuronium?
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چکیده
Methods. One hundred ASA I and II patients were randomized to receive 1 MAC of desflurane or sevoflurane during manual ventilation or not. Anaesthesia was induced with an effect-sitecontrolled infusion of remifentanil at 2 ng ml 1 for 3 min. Patients then received propofol to induce loss of consciousness (LOC). Rocuronium (0.6 mg kg ) was given at LOC and the trachea was intubated after 90 s of manual breathing support (=baseline) with or without inhaled anaesthetics. Vital signs and bispectral index (BIS) were recorded until 10 min post-intubation to detect autonomic and arousal response.
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